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Key words: 3d graphing software, scientific graphing software, math graphing software
Ligand Binding Module - SigmaPlot Module
Analyze and plot ligand / receptor and dose response data quickly and easily
Automatically fit radioligand and dose response equations for multiple compounds with replicate data. Select the type of study in the customized dialog and specify the number of replicate values to instantly
plot and analyze your data. All graphs and analysis appear as notebook items, to efficiently manage your work.
Select from a wide range of models to determine parameter values
Choose from ten built-in equations, create a new equation or modify an existing equation to analyze the number of binding sites, and their affinity for various drugs. Fit one and
two site saturation equations to determine the number of binding sites, Bmax, and the ligand affinity, Kd. Fit competition and sigmoidal dose-response equations to learn the affinity of
the receptor for the competing molecule, EC50, or specify ligand concentration and Kd to generate Ki, the equilibrium dissociation constant Automatically
generate a report with the equation fit results and the associated error analysis.
Save time by plotting multiple compounds simultaneously
Automatically generate a plot of mean response versus concentration and include the best-fit lines for each compound. Modify your graph as desired to
present your results exactly the way you want. Specify the fit range, minimum and maximum x values, to customize your analysis. Clearly distinguish different compounds with symbols and legends.
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